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    The use of isotretinoin, the active ingredient in the acne medicine Accutane, is believed to more than double the risk of depression.  In a report in the Journal of Clinical Psychiatry, Doctors from CHU Sainte-Justine Research Centre in Montreal have performed the first study to find a statistically significant link between isotretinoin and depression.

    While depression is likely to be a rare side effect of isotretinoin, current guidelines should be modified to include psychiatric assessments before and during a patients use of Accutane.  

    If you or a loved one have taken Accutane here are some common symptoms of depression to look for:

        1.  Loss of interest in daily activities

        2.  Loss of appetite or weight changes

        3.  Changes in sleep

        4.  Loss of energy

        5.  Concentration problems

        6.  Irritability

        7.  Aches and pains

    People suffering from depression often show distorted thinking.  Everything looks bleak to them, and they hold extremely negative views about themselves, their situation, and the future.  Trapped in their pessimism, they obsess over their problems and blow them out of proportion.  Unable to see a light at the end of the tunnel, they may even start to see suicide as their only way out.

    For more information on depression, please check out the Dr. Robert E. Elliott Foundation at

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